A new study on EIPH and Salix

Abstracts have just been released for the upcoming Equine Science Society Symposium to be held in New Mexico at the end of May. Among the abstracts is a very interesting paper on EIPH completed by Dr Joe Pagan and colleagues. The abstract reads: Furosemide reduces the energetic cost of exercise in Thoroughbreds independent of its effect on EIPH J.D. Pagan, B.M. Waldridge, C. Whitehouse, L. Dalglish, S. Fuchs, and M. Goff Kentucky Equine Research, Inc., Versailles, KY 40383 Six fit Thoroughbred geldings (age 6.8, BW 585kg) were used in a 3 by 3 Latin square trial to test the effect of furosemide on energetic efficiency during a standardized exercise test (SET) on an inclined (30) high-speed t

Hydrogen water and β-adrenergic receptors

There have been a couple of interesting scientific papers released in recent days, one on horses and the use of hydrogen-rich water and oxidative stress, the other on β-adrenergic receptor polymorphisms within the ADRB2 gene as it relates to power/sprint performance in humans. Effect of Treadmill Exercise and Hydrogen-rich Water Intake on Serum Oxidative and Anti-oxidative Metabolites in Serum of Thoroughbred Horses - The present study aimed to clarify changes of oxidative stress and antioxidative functions in treadmill-exercised Thoroughbred horses (n=5, 3 to 7 years old), using recently developed techniques for measurement of serum d-ROMs for oxidative stress, and BAP for antioxidative mar

All Natural EPO.....is that possible?

First of all....a little lesson for some background. It is well established in exercise physiology that an increase in EPO production may result in an increase in the number of red blood cells (RBC) and thus an increase in oxygen transport capacity of the blood and that an increase in oxygen transport capacity may result in an increase in the ability to perform endurance exercise. The whole process relies upon the production of volume of red blood cells. The total mass of RBCs in the circulatory system is regulated within narrow limits in order to maintain sufficient tissue oxygenation and to prevent deleterious effects of severe hemoconcentration (that is too many RBCs for the blood volume

Hypoxic sprint training

A few weeks back I posted about how the Australian Racing Board had seen fit to investigate the use of hypoxic training in thoroughbreds. I noted at the time that there was some conjecture as to the efficacy of training in hypoxia with some studies reporting its success and others not. A study that appeared last week in the Medicine & Science in Sports & Exercise journal seems to fall in the "does not" category. The study compared the effect of sprint interval training in normoxia versus hypoxia on muscle glycolytic and oxidative capacity, monocarboxylate transporter content, and endurance exercise performance in humans and found that while sprint interval training in hypoxia upregulated the

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